About half of all the people admitted to emergency rooms in the U. as a result of nonmedical use of sedatives have a legitimate prescription for the drug, but have taken an excessive dose or combined it with alcohol or other drugs.
Intensive care unit patients who receive higher doses over longer periods, typically via IV drip, are more likely to experience such side effects.
Sedatives — most commonly alcohol — have been reported for their use as date rape drugs (also called a Mickey) and being administered to unsuspecting patrons in bars or guests at parties to reduce the intended victims' defenses. Statistical overviews suggest that the use of sedative-spiked drinks for robbing people is actually much more common than their use for rape., as the loss of inhibitions from the drug may increase their confidence to commit the offence, and the amnesia produced by the drug makes it difficult for police to interrogate them if they are caught.
More horses than ever are living into their 30s, thanks to improving veterinary care and the fierce determination of owners to provide their loved companions with a happy and healthy retirement.
Exactly when a horse should be considered old will vary greatly.
Malcolm Lader at the Institute of Psychiatry in London estimates the incidence of these adverse reactions at about 5%, even in short-term use of the drugs.
The paradoxical reactions may consist of depression, with or without suicidal tendencies, phobias, aggressiveness, violent behavior and symptoms sometimes misdiagnosed as psychosis.Some heroin users may take them either to supplement their drug or to substitute for it.Stimulant users may take sedatives to calm excessive jitteriness.Although sedatives do not relieve pain in themselves, they can be a useful adjunct to analgesics in preparing patients for surgery, and are commonly given to patients before they are anaesthetized, or before other highly uncomfortable and invasive procedures like cardiac catheterization, colonoscopy or MRI.They increase tractability and compliance of children or troublesome or demanding patients.At higher doses it may result in slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes.